Products for Research Use Only
RegisterLogin

CD8a Antibody [OKT8] (APC)

CAT: 0223-76-674Size: 500 TestsDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-76-674Size:500 Tests
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32-34 kDa. CD8alpha is a member of the Ig superfamily, expressed as a homodimer (CD8alphaalpha) or as a heterodimer (CD8alphabeta) . CD8+ alphabeta T lymphocytes express both CD8alphaalpha and CD8alphabeta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes.OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.
NCBI Gene ID
925
Swiss Prot
P01732
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
OKT8
Conjugation
APC
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG2a
Specificity
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32-34 kDa.
Symbol
CD8A
NCBI Official Name
CD8a molecule
NCBI Organism
Homo sapiens
Background Reference 01
Ledbetter, J. A., Herzenberg, L. A. (1979) . Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*.Immunological reviews,47 (1), 63-90.
Background Reference 02
Ledbetter, J. A., Rouse, R. V., Micklem, H. S., Herzenberg, L. A. (1980) . T cell subsets defined by expression of Lyt-1, 2, 3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.The Journal of experimental medicine,152 (2), 280-295.
Background Reference 03
Hathcock, K. (1991) . T cell enrichment by cytotoxic elimination of B cells and accessory cells.Current protocols in immunology, 3-3.
Other Product Names
CD8, MAL, p32, Leu2, CD8A
Tested Applications
Flow
Physical Properties
Liquid

Related Products

CatalogName
76-664CD8a Antibody [OKT8] (FITC)
76-667CD8a Antibody [OKT8] (PE)
76-666CD8a Antibody [OKT8] (PE)
76-665CD8a Antibody [OKT8] (PE)
76-663CD8a Antibody [OKT8] (FITC)
76-662CD8a Antibody [OKT8] (FITC)
76-671CD8a Antibody [OKT8] (PE-Cy7)
76-661CD8a Antibody [OKT8] (Violet-450)
76-660CD8a Antibody [OKT8] (Violet-450)
76-670CD8a Antibody [OKT8] (PE-Cy7)

Alternative Products

CatalogName
MBS4165242-01APC Anti-Human CD8a (OKT8)
QAB17-APC-500TestsAnti-CD8a Antibody [OKT8], APC-500Tests
QAB17-APC-100TestsAnti-CD8a Antibody [OKT8], APC-100Tests
QAB17-APC-25TestsAnti-CD8a Antibody [OKT8], APC-25Tests
ARO-A10411-01Anti-Human CD8a/Lyt2 Antibody (OKT8), APC
A1583-100Anti-Human CD8a PE Antibody (OKT8)
QAB17-F-500TestsAnti-CD8a Antibody [OKT8], FITC-500Tests
QAB17-F-100TestsAnti-CD8a Antibody [OKT8], FITC-100Tests
HF815207Anti-Human CD8a/Lyt2 Antibody (OKT8)
QAB17-F-25TestsAnti-CD8a Antibody [OKT8], FITC-25Tests

Popular Products