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CD3 Antibody [SK7] (APC)

CAT: 0223-76-305Size: 25 TestsDry Ice: NoHazardous: No
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CAT#:0223-76-305Size:25 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The SK7 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. The SK7 antibody is reported to have a mitogenic effect on the majority of peripheral blood T cells in the presence of functional monocytes.
NCBI Gene ID
916
Swiss Prot
P07766
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
SK7
Conjugation
APC
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The SK7 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex.
Symbol
CD3E
NCBI Official Name
CD3e molecule, epsilon (CD3-TCR complex)
NCBI Organism
Homo sapiens
Background Reference 01
Van Dongen, J. J., Krissansen, G. W., Wolvers-Tettero, I. L., Comans-Bitter, W. M., Adriaansen, H. J., Hooijkaas, H., ... Terhorst, C. (1988) . Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies.Blood,71 (3), 603-612.
Background Reference 02
Haynes, B. F. (1986) . Summary of T cell studies performed during the second international workshop and conference on human leukocyte differentiation antigens. InLeukocyte typing II (pp. 3-30) . Springer New York.
Background Reference 03
Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... A't Hart, B. (2009) . A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.Journal of Histochemistry Cytochemistry,57 (12), 1159-1167.
Other Product Names
T3E, TCRE, IMD18, CD3E
Tested Applications
Flow
Physical Properties
Liquid

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Alternative Products

CatalogName
100331C0-AATAPC Anti-human CD3 Antibody *SK7*
QAB4-APC-500TestsAnti-CD3 Antibody [SK7], APC-500Tests
QAB4-APC-100TestsAnti-CD3 Antibody [SK7], APC-100Tests
QAB4-APC-25TestsAnti-CD3 Antibody [SK7], APC-25Tests
100331E1-AATAPC/XFD750 Anti-human CD3 Antibody *SK7*
100331D1-AATAPC/Cy7 Anti-human CD3 Antibody *SK7*
QAB4-APC7-25TestsAnti-CD3 Antibody [SK7], APC-Cy7-25Tests
QAB4-APC7-100TestsAnti-CD3 Antibody [SK7], APC-Cy7-100Tests
100331F2-AATAPC/iFluor® 700 Anti-human CD3 Antibody *SK7*
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