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CD61 Antibody [VI-PL2]

CAT: 0223-76-176Size: 0.025 mgDry Ice: NoHazardous: No
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CAT#:0223-76-176Size:0.025 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV) . It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
NCBI Gene ID
3690
Swiss Prot
P05106
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
VI-PL2
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3.
Symbol
ITGB3
NCBI Official Name
Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
NCBI Organism
Homo sapiens
Background Reference 01
Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.
Background Reference 02
Barrett, L., Dai, C., Gamberg, J., Gallant, M., Grant, M. (2007) . Circulating CD14 CD36+ peripheral blood mononuclear cells constitutively produce interleukin-10.Journal of leukocyte biology,82 (1), 152-160.
Background Reference 03
Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Other Product Names
GT, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16, ITGB3
Tested Applications
Flow, IHC, Functional Assays, WB
Physical Properties
Liquid

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