STAT5A (phospho Ser780) Antibody

• Background:

  Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.

• NCBI Gene ID:

  6776

• Swiss Prot:

  P42229

• Accession Number:

  NP_003143.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  STAT5A (Phospho-Ser780) antibody was raised against a peptide sequence around phosphorylation site of serine 780 (R-L-S (p) -P-P) derived from Human STAT5A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  90 kDa

• Specificity:

  This antibody detects endogenous level of STAT5A only when phosphorylated at serine 780.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

• Symbol:

  STAT5A

• NCBI Official Name:

  Signal transducer and activator of transcription 5A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369. Dentelli P, et al. (1999) J Immunol. 163: 2151-2159. Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.

• Other Product Names:

  MGF, STAT5, JAK1A, JAK1B, MGF, MPF, Mammary gland factor, STA5ASTAT5

• Tested Applications:

  WB, IHC

• Protein ID:

  21618342

• Physical Properties:

  Liquid