CD8 Antibody [RAVB3]

• Background :

  CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.

• NCBI Gene ID :

  925

• Swiss Prot :

  P01732

• Accession Number :

  P01732

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  Ni-NTA purified recombinant human CD8 expressed in E. Coli strain BL21 (DE3) .

• Clonality :

  Monoclonal

• Clone :

  RAVB3

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology

• Purification :

  Antibody is purified by protein A affinity chromatography.

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody in PBS containing 0.03% sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  CD8 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment :

  IgG1

• Symbol :

  CD8A

• NCBI Official Name :

  CD8a molecule

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Veillette, A. et al. 1988. Cell 55:301.

• Other Product Names :

  MALCD8, MAL, p32, Leu2

• Tested Applications :

  ELISA, WB

• Protein ID :

  116035