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CD8 Antibody [C8/1035]

CAT: 0223-33-279Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-33-279Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cluster of Differentiation 8 is a cell surface receptor expressed either as a heterodimer with the beta chain or as a homodimer. A majority of thymocytes and a subpopulation of mature Tcells and NK cells express CD8a. It binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in Tcell development and activation of mature Tcells. For mature Tcells, CD4 and 8 are mutually exclusive, so antibody to CD8 is generally used in conjunction with antibody to CD4.
NCBI Gene ID
925
Swiss Prot
P01732
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human CD8a protein was used as immunogen for this anti-CD8 antibody.
Clonality
Monoclonal
Clone
C8/1035
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
CD8A
NCBI Official Name
CD8a molecule
NCBI Organism
Homo sapiens
Other Product Names
T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL
Tested Applications
WB, Flow, IF
Physical Properties
Liquid

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