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HADHB Antibody

CAT: 0223-64-152Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-152Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HADHB encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
NCBI Gene ID
3032
Swiss Prot
P55084
Accession Number
P55084
Host
Rabbit
Reactivity
Human
Immunogen
This HADHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-342 amino acids from the C-terminal region of human HADHB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
HADHB
NCBI Official Name
Trifunctional enzyme subunit beta, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Purevsuren, J., et al. Mol. Genet. Metab. 98 (4) :372-377 (2009)
Background Reference 02
Bogenhagen, D.F., et al. J. Biol. Chem. 283 (6) :3665-3675 (2008)
Background Reference 03
Wang, R., et al. Zhonghua Fu Chan Ke Za Zhi 41 (10) :672-675 (2006)
Background Reference 04
Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)
Other Product Names
Trifunctional enzyme subunit beta, mitochondrial, TP-beta, 3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, HADHB
Tested Applications
WB, Flow
Protein ID
116241345
Physical Properties
Liquid

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