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GPR17 Antibody

CAT: 0223-64-147Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-147Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of the G protein coupled receptor (GPCR) superfamily contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The organization of the GPR17 gene differs from that of many other GPCRs in that the open reading frame is distributed on 2 exons; an additional exon contains the 5 prime untranslated region. Human GPR17 is expressed as 2.3 and 6.3 kb mRNAs exclusively in brain. The 2 transcripts appear to represent alternatively polyadenylated variants. Based on protein sequence homology and the conservation of certain key residues, GPR17 appears to be closely related to the P2Y family of GPCRs. There are two nemed isoforms.
NCBI Gene ID
2840
Swiss Prot
Q13304
Accession Number
Q13304
Host
Rabbit
Reactivity
Human
Immunogen
This GPR17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-258 amino acids from the Central region of human GPR17.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
GPR17
NCBI Official Name
Uracil nucleotide/cysteinyl leukotriene receptor
NCBI Organism
Homo sapiens
Background Reference 01
Pugliese, A.M., et al. Am. J. Physiol., Cell Physiol. 297 (4), C1028-C1040 (2009)
Background Reference 02
Parravicini, C., et al. BMC Bioinformatics 9, 263 (2008)
Background Reference 03
Ciana, P., et al. EMBO J. 25 (19) :4615-4627 (2006)
Other Product Names
Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT receptor, G-protein coupled receptor 17, P2Y-like receptor, R12, GPR17
Tested Applications
WB, IHC-P, Flow
Protein ID
21264435
Physical Properties
Liquid

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