RXRB Antibody

• Background:

  This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA) . This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.

• NCBI Gene ID:

  6257

• Swiss Prot:

  P28702

• Accession Number:

  P28702

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RXRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-284 amino acids from the Central region of human RXRB.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  57 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RXRB

• NCBI Official Name:

  Retinoic acid receptor RXR-beta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)

• Background Reference 02:

  Hosgood, H.D. III, et al. Respir Med 103 (12) :1866-1870 (2009)

• Background Reference 03:

  Barcellos, L.F., et al. PLoS Genet. (10), E1000696 (2009)

• Background Reference 04:

  Kalsch, A.I., et al. Autoimmunity 42 (5) :467-474 (2009)

• Other Product Names:

  Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2, Retinoid X receptor beta, RXRB, NR2B2

• Tested Applications:

  WB

• Protein ID:

  1350911

• Physical Properties:

  Liquid