RXRA Antibody

CAT: 0223-61-713Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-713Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.
NCBI Gene ID
6256
Swiss Prot
P19793
Accession Number
P19793
Host
Rabbit
Reactivity
Human
Immunogen
This RXRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human RXRA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
RXRA
NCBI Official Name
Retinoic acid receptor RXR-alpha
NCBI Organism
Homo sapiens
Background Reference 01
Egan, J.B., et al. Cancer Res. 70 (4) :1496-1504 (2010)
Background Reference 02
Qiu, J.J., et al. Blood 115 (3) :643-652 (2010)
Background Reference 03
Neugebauer, P., et al. Vnitr Lek 55 (12) :1135-1140 (2009)
Other Product Names
Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha, RXRA, NR2B1
Tested Applications
WB, IHC-P
Protein ID
133701
Physical Properties
Liquid

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