RXRA Antibody

• Background:

  Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.

• NCBI Gene ID:

  6256

• Swiss Prot:

  P19793

• Accession Number:

  P19793

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RXRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human RXRA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RXRA

• NCBI Official Name:

  Retinoic acid receptor RXR-alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Egan, J.B., et al. Cancer Res. 70 (4) :1496-1504 (2010)

• Background Reference 02:

  Qiu, J.J., et al. Blood 115 (3) :643-652 (2010)

• Background Reference 03:

  Neugebauer, P., et al. Vnitr Lek 55 (12) :1135-1140 (2009)

• Other Product Names:

  Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha, RXRA, NR2B1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  133701

• Physical Properties:

  Liquid