ADH7 Antibody

• Background:

  This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members.

• NCBI Gene ID:

  131

• Swiss Prot:

  P40394

• Accession Number:

  P40394

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ADH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the C-terminal region of human ADH7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  41 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ADH7

• NCBI Official Name:

  Alcohol dehydrogenase class 4 mu/sigma chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kedishvili, N.Y., et al. J. Biol. Chem. 270 (8) :3625-3630 (1995)

• Background Reference 02:

  Cheung, B., et al. Alcohol. Clin. Exp. Res. 19 (1) :185-186 (1995)

• Background Reference 03:

  Farres, J., et al. Eur. J. Biochem. 224 (2) :549-557 (1994)

• Background Reference 04:

  Pares, X., et al. FEBS Lett. 303 (1) :69-72 (1992)

• Other Product Names:

  Alcohol dehydrogenase class 4 mu/sigma chain, Alcohol dehydrogenase class IV mu/sigma chain, Gastric alcohol dehydrogenase, Retinol dehydrogenase, ADH7

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  292495000

• Physical Properties:

  Liquid