ADH7 Antibody

CAT: 0223-64-074Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-64-074Size:400 µL
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Background
This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members.
NCBI Gene ID
131
Swiss Prot
P40394
Accession Number
P40394
Host
Rabbit
Reactivity
Human
Immunogen
This ADH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the C-terminal region of human ADH7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
ADH7
NCBI Official Name
Alcohol dehydrogenase class 4 mu/sigma chain
NCBI Organism
Homo sapiens
Background Reference 01
Kedishvili, N.Y., et al. J. Biol. Chem. 270 (8) :3625-3630 (1995)
Background Reference 02
Cheung, B., et al. Alcohol. Clin. Exp. Res. 19 (1) :185-186 (1995)
Background Reference 03
Farres, J., et al. Eur. J. Biochem. 224 (2) :549-557 (1994)
Background Reference 04
Pares, X., et al. FEBS Lett. 303 (1) :69-72 (1992)
Other Product Names
Alcohol dehydrogenase class 4 mu/sigma chain, Alcohol dehydrogenase class IV mu/sigma chain, Gastric alcohol dehydrogenase, Retinol dehydrogenase, ADH7
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
292495000
Physical Properties
Liquid

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