ADH5 Antibody

• Background :

  ADH5 is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis.

• NCBI Gene ID :

  128

• Swiss Prot :

  P11766

• Accession Number :

  P11766

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ADH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-239 amino acids from the Central region of human ADH5.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Rb

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  40 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ADH5

• NCBI Official Name :

  Alcohol dehydrogenase class-3

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Martins-de-Souza, D., et.al., Eur Arch Psychiatry Clin Neurosci 259 (3), 151-163 (2009)

• Background Reference 02 :

  Iborra, F.J., et.al., J. Histochem. Cytochem. 40 (12), 1865-1878 (1992)

• Other Product Names :

  HGNC:253

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  113408

• Physical Properties :

  Liquid