NOXA1 Antibody

CAT: 0223-64-008Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-64-008Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS) . The NOX activator NOXA1 can stimulate both NOX1 (MIM 300225) and NOX2 (CYBB; MIM 300481), but it appears to be more effective in activating NOX1 (Opitz et al., 2007 [PubMed 17189823]) .[supplied by OMIM].
NCBI Gene ID
10811
Swiss Prot
Q86UR1
Accession Number
Q86UR1
Host
Rabbit
Reactivity
Human
Immunogen
This NOXA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-478 amino acids from the C-terminal region of human NOXA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NOXA1
NCBI Official Name
NADPH oxidase activator 1
NCBI Organism
Homo sapiens
Background Reference 01
Niu, X.L., et al. Circulation 121 (4) :549-559 (2010)
Background Reference 02
Pacquelet, S., et al. J. Biol. Chem. 283 (36) :24649-24658 (2008)
Background Reference 03
Honjo, T., et al. Endothelium 15 (3) :137-141 (2008)
Background Reference 04
Kim, J.S., et al. J. Biol. Chem. 282 (48) :34787-34800 (2007)
Other Product Names
NADPH oxidase activator 1, NOX activator 1, Antigen NY-CO-31, NCF2-like protein, P67phox-like factor, p51-nox, NOXA1, P51NOX
Tested Applications
WB
Protein ID
74759404
Physical Properties
Liquid

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