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CEBPA Antibody

CAT: 0223-63-967Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-967Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
NCBI Gene ID
1050
Swiss Prot
P49715
Accession Number
P49715
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CEBPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-330 amino acids from the C-terminal region of human CEBPA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Symbol
CEBPA
NCBI Official Name
CCAAT/enhancer-binding protein alpha
NCBI Organism
Homo sapiens
Background Reference 01
Twu, Y.C., et al. Blood 115 (12) :2491-2499 (2010)
Background Reference 02
Nanri, T., et al. Genes Chromosomes Cancer 49 (3) :237-241 (2010)
Background Reference 03
Burnett, A.K., et al. Blood 115 (5) :948-956 (2010)
Background Reference 04
Dufour, A., et al. J. Clin. Oncol. 28 (4) :570-577 (2010)
Other Product Names
CCAAT/enhancer-binding protein alpha, C/EBP alpha, CEBPA
Tested Applications
WB, Flow
Protein ID
166898082
Physical Properties
Liquid

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