CEBPD Antibody

• Background:

  CEBPD Antibody: CCAAT enhancer binding proteins (CEBPs) are a family of transcription factors that all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. At least six members of the family have been isolated and characterized to date (CEBP alpha to CEBP zeta) . CEBPD is a leucine zipper (LZ) DNA-binding protein that regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. CEBPD is an important transcriptional activator in the regulation of genes involved in immune and inflammatory responses and has been reported to possess many tumor suppressor-like properties.

• NCBI Gene ID:

  1052

• Swiss Prot:

  P49716

• Accession Number:

  NP_005186

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  CEBPD Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 1466 - Rat Spleen Tissue Lysate

• Concentration:

  1 mg/mL

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine: (100%), Sheep: (100%)

• Buffer:

  CEBPD Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  CEBPD antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  30 kDa

• Fragment:

  IgG

• Specificity:

  Multiple transcript variants encoding different isoforms have been found for this gene.

• Symbol:

  CEBPD

• Positive Control 2:

  Cat. No. 10-901 - Human Spleen Tissue Slide

• NCBI Official Name:

  CCAAT/enhancer binding protein (C/EBP), delta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Williams SC, Cantwell CA, Johnson PF, et al. A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. Genes Dev.1991; 5:1553-67.

• Background Reference 02:

  Umek RM, Friedman AD, and McKnight SL. CCAAT-enhancer binding protein: a component of a differentiation switch. Science 1991; 251:288-92.

• Background Reference 03:

  Ramji DP and Foka P. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem. J. 2002; 365:561-75.

• Background Reference 04:

  Johnson PF, Landschulz WH, Graves BJ, et al. Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes Dev. 1987; 1:133-46.

• Other Product Names:

  CEBPD Antibody: CELF, CRP3, C/EBP-delta, NF-IL6-betaNuclear factor NF-IL6-beta, NF-IL6-beta

• Tested Applications:

  ELISA, WB, IF

• Protein ID:

  28872798

• Physical Properties:

  Liquid