RPLP2 Antibody

• Background:

  RPLP2 consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

• NCBI Gene ID:

  6181

• Swiss Prot:

  P05387

• Accession Number:

  P05387

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RPLP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human RPLP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  12 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RPLP2

• NCBI Official Name:

  60S acidic ribosomal protein P2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Martinez-Azorin, F. FEBS Lett. 582 (20), 3029-3032 (2008) Martinez-Azorin, F. Biochem. J. 413 (3), 527-534 (2008) Sugiyama, N. Mol. Cell Proteomics (6), 1103-1109 (2007)

• Other Product Names:

  60S acidic ribosomal protein P2, Renal carcinoma antigen NY-REN-44, RPLP2, D11S2243E, RPP2

• Tested Applications:

  WB

• Physical Properties:

  Liquid