DDX17 Antibody

• Background:

  DDX17 box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This protein encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family.

• NCBI Gene ID:

  10521

• Swiss Prot:

  Q92841

• Accession Number:

  Q92841

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DDX17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the N-terminal region of human DDX17.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  80 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  DDX17

• NCBI Official Name:

  Probable ATP-dependent RNA helicase DDX17

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wortham, N.C., et.al., Oncogene 28 (46), 4053-4064 (2009)

• Background Reference 02:

  Tonevitsky, E.A., et.al., Bull. Exp. Biol. Med. 147 (6), 733-736 (2009)

• Background Reference 03:

  Wong, H.Y., et.al., Biochim. Biophys. Acta 1794 (2), 193-198 (2009)

• Other Product Names:

  Probable ATP-dependent RNA helicase DDX17, DEAD box protein 17, DEAD box protein p72, RNA-dependent helicase p72, DDX17

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid