PPP2R2B Antibody

• Background:

  PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.

• NCBI Gene ID:

  5521

• Swiss Prot:

  Q00005

• Accession Number:

  Q00005

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPP2R2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-130 amino acids from the Central region of human PPP2R2B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  52 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PPP2R2B

• NCBI Official Name:

  Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rajkiewicz, M., et.al., Neurol. Neurochir. Pol. 42 (6), 497-504 (2008)

• Background Reference 02:

  Ben-Israel, H., et.al., J. Virol. 82 (19), 9381-9388 (2008)

• Background Reference 03:

  Strack, S., et.al., J. Comp. Neurol. 392 (4), 515-527 (1998)

• Other Product Names:

  Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, PP2A subunit B isoform B55-beta, PP2A subunit B isoform PR55-beta, PP2A subunit B isoform R2-beta, PP2A subunit B isoform beta, PPP2R2B

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  231446

• Physical Properties:

  Liquid