YWHAZ Antibody

• Background:

  14-3-3 protein zeta/delta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs.

• NCBI Gene ID:

  7534

• Swiss Prot:

  P63104

• Accession Number:

  P63104

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from human YWHAZ.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  YWHAZ

• NCBI Official Name:

  14-3-3 protein zeta/delta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, F.Q., J. Cell Biol. 181 (7), 1141-1154 (2008)

• Background Reference 02:

  Mateo, I., Eur. J. Neurol. 15 (3), 219-222 (2008)

• Background Reference 03:

  Li, Z., Proc. Natl. Acad. Sci. U.S.A. 105 (1), 162-167 (2008)

• Background Reference 04:

  Powell, D.W., Mol. Cell. Biol. 23 (15), 5376-5387 (2003)

• Other Product Names:

  14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ

• Tested Applications:

  WB, IHC-P

• Protein ID:

  52000887

• Physical Properties:

  Liquid