Diacylglycerol kinase iota Antibody

• Background:

  DGKI a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration.

• NCBI Gene ID:

  9162

• Swiss Prot:

  O75912

• Accession Number:

  O75912

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Diacylglycerol kinase iota (DGKI) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 890-920 amino acids from the C-terminal region of human Diacylglycerol kinase iota (DGKI) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  117 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  DGKI

• NCBI Official Name:

  Diacylglycerol kinase iota

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ding, L., et al., J. Biol. Chem. 273 (49) :32746-32752 (1998) .

• Background Reference 02:

  Bowne, S.J., et al., Mol. Vis. 6, 6-9 (2000) .

• Other Product Names:

  Diacylglycerol kinase iota, DAG kinase iota, Diglyceride kinase iota, DGK-iota, DGKI

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid