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MLK2 Antibody

CAT: 0223-63-288Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-288Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MLK2 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
NCBI Gene ID
4294
Swiss Prot
Q02779
Accession Number
Q02779
Host
Rabbit
Reactivity
Human
Immunogen
This MLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 628-659 amino acids from the C-terminal region of human MLK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
104 kDa
Fragment
Rabbit Ig
Symbol
MAP3K10
NCBI Official Name
Mitogen-activated protein kinase kinase kinase 10
NCBI Organism
Homo sapiens
Background Reference 01
Dorow, D.S., et al., Eur. J. Biochem. 234 (2) :492-500 (1995) .
Background Reference 02
Katoh, M., et al., Oncogene 10 (7) :1447-1451 (1995) .
Background Reference 03
Dorow, D.S., et al., Eur. J. Biochem. 213 (2) :701-710 (1993) .
Other Product Names
Mitogen-activated protein kinase kinase kinase 10, Mixed lineage kinase 2, Protein kinase MST, MAP3K10, MLK2, MST
Tested Applications
WB, IHC-P
Protein ID
145559494
Physical Properties
Liquid

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