VARS Antibody

• Background:

  Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. This protein belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.

• NCBI Gene ID:

  7407

• Swiss Prot:

  P26640

• Accession Number:

  P26640

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This VARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human VARS.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  140 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  VARS

• NCBI Official Name:

  Valine--tRNA ligase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jiang, S., FEBS Lett. 579 (27), 6049-6054 (2005)

• Background Reference 02:

  Bonnefond, L., Biochemistry 44 (12), 4805-4816 (2005)

• Background Reference 03:

  Xie, T., Genome Res. 13 (12), 2621-2636 (2003)

• Other Product Names:

  Valine--tRNA ligase, Protein G7a, Valyl-tRNA synthetase, ValRS, VARS, G7A, VARS2

• Tested Applications:

  WB

• Protein ID:

  12644177

• Physical Properties:

  Liquid