NGFB Antibody

• Background:

  NGFB is a member of the NGF-beta family. It is a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in the gene encoding NGFB have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of the gene's expression is associated with allergic rhinitis.

• NCBI Gene ID:

  4803

• Swiss Prot:

  P01138

• Accession Number:

  P01138

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-115 amino acids from the Central region of human NGFB.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  27 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NGF

• NCBI Official Name:

  Beta-nerve growth factor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lang, U.E., Pharmacopsychiatry 41 (5), 196-199 (2008)

• Background Reference 02:

  Truzzi, F., J. Invest. Dermatol. 128 (8), 2031-2040 (2008)

• Background Reference 03:

  MacGrogan, D., J. Neurochem. 59 (4), 1381-1391 (1992)

• Other Product Names:

  Beta-nerve growth factor, Beta-NGF, NGF, NGFB

• Tested Applications:

  WB, IHC-P, IF, Flow

• Physical Properties:

  Liquid