ERBB3 Antibody

CAT: 0223-63-071Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-071Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
ErbB3, a member of the EGF receptor family, binds and is activated by neuregulins and NTAK. It potentially forms a heterodimer with each of the other ERBB receptors. This protein is predominantly expressed in epithelial tissues and brain. The cytoplasmic part of the receptor may interact with the SH2 or SH3 domains of many signal-transducing proteins. Ligand-binding may increase phosphorylation on tyrosine residues and promote its association with the p85 subunit of phosphatidylinositol 3-kinase ErbB3 is overexpressed in a subset of human mammary tumors.
NCBI Gene ID
2065
Swiss Prot
P21860
Accession Number
P21860
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ERBB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-55 amino acids from the N-terminal region of human ERBB3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
148 kDa
Fragment
Rabbit Ig
Symbol
ERBB3
NCBI Official Name
Receptor tyrosine-protein kinase erbB-3
NCBI Organism
Homo sapiens
Background Reference 01
Katoh, M., et al., Biochem. Biophys. Res. Commun. 192 (3) :1189-1197 (1993) . Plowman, G.D., et al., Proc. Natl. Acad. Sci. U.S.A. 87 (13) :4905-4909 (1990) . Kraus, M.H., et al., Proc. Natl. Acad. Sci. U.S.A. 86 (23) :9193-9197 (1989) .
Other Product Names
Receptor tyrosine-protein kinase erbB-3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, ERBB3, HER3
Tested Applications
WB, IHC-P, Flow
Protein ID
119534
Physical Properties
Liquid

Related Products

CatalogName
45-050PERBB3 Peptide
10-862Zenocutuzumab (ERBB2/ERBB3) - Research Grade Biosimilar
79-420Her3 / ErbB3 (Ab 1328) Antibody
79-689Her3 / ErbB3 (Ab 1289) Antibody
79-241Her3 / ErbB3 (phospho Tyr1328) Antibody
91-962ErbB3 Recombinant Protein
11-235ErbB3 / Her3 Recombinant Protein
11-291ErbB3 / Her3 Recombinant Protein
11-381ErbB3 / Her3 Recombinant Protein
11-544ErbB3 / Her3 Recombinant Protein

Alternative Products

CatalogName
10-2519ErbB3 antibody

Popular Products