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CSNK1D Antibody

CAT: 0223-62-884Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-884Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The casein kinase 1 (CK1) group consists of 12 kinases including CK1, TTBK (tau tubulin kinase), and VRK (vaccinia-related kinase) families. The receptor guanylate cyclase (RGC) group consists of 5 kinases similar in domain sequence to TKs (ANP, CYG) .
NCBI Gene ID
1453
Swiss Prot
P48730
Accession Number
P48730
Host
Rabbit
Reactivity
Human
Immunogen
This CSNK1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-352 amino acids from the C-terminal region of human CSNK1D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
CSNK1D
NCBI Official Name
Casein kinase I isoform delta
NCBI Organism
Homo sapiens
Background Reference 01
Sillibourne, J.E., et al., J. Mol. Biol. 322 (4) :785-797 (2002) .
Background Reference 02
Rivers, A., et al., J. Biol. Chem. 273 (26) :15980-15984 (1998) .
Background Reference 03
Kusuda, J., et al., Genomics 32 (1) :140-143 (1996) .
Background Reference 04
Fish, K.J., et al., J. Biol. Chem. 270 (25) :14875-14883 (1995) .
Other Product Names
Casein kinase I isoform delta, CKI-delta, CKId, Tau-protein kinase CSNK1D, CSNK1D, HCKID
Tested Applications
WB, IHC-P
Protein ID
27923980
Physical Properties
Liquid

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