Mouse Csnk1e Antibody

• Background:

  Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.

• NCBI Gene ID:

  27373

• Swiss Prot:

  Q9JMK2

• Accession Number:

  Q9JMK2

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Csnk1e antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-310 amino acids from the C-terminal region of mouse Csnk1e.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Human

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  47 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  Csnk1e

• NCBI Official Name:

  Casein kinase I isoform epsilon

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Meng, Q.J., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (34) :15240-15245 (2010)

• Background Reference 02:

  Sugiyama, Y., et al. Biochem. J. 427 (3) :489-497 (2010)

• Background Reference 03:

  Etchegaray, J.P., et al. PLoS ONE (4), E10303 (2010) :

• Background Reference 04:

  Lee, H., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (50) :21359-21364 (2009)

• Other Product Names:

  Casein kinase I isoform epsilon, CKI-epsilon, CKIe, Csnk1e

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid