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Mouse Csnk1e Antibody

CAT: 0223-57-926Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-926Size:400 µL
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Background
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.
NCBI Gene ID
27373
Swiss Prot
Q9JMK2
Accession Number
Q9JMK2
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Csnk1e antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-310 amino acids from the C-terminal region of mouse Csnk1e.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Human
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
Csnk1e
NCBI Official Name
Casein kinase I isoform epsilon
NCBI Organism
Mus musculus
Background Reference 01
Meng, Q.J., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (34) :15240-15245 (2010)
Background Reference 02
Sugiyama, Y., et al. Biochem. J. 427 (3) :489-497 (2010)
Background Reference 03
Etchegaray, J.P., et al. PLoS ONE (4), E10303 (2010) :
Background Reference 04
Lee, H., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (50) :21359-21364 (2009)
Other Product Names
Casein kinase I isoform epsilon, CKI-epsilon, CKIe, Csnk1e
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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