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MAPE Antibody

CAT: 0223-62-428Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-428Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.
NCBI Gene ID
23532
Swiss Prot
P78395
Accession Number
P78395
Host
Rabbit
Reactivity
Human
Immunogen
This MAPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human MAPE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Symbol
PRAME
NCBI Official Name
Melanoma antigen preferentially expressed in tumors
NCBI Organism
Homo sapiens
Background Reference 01
Rezvani, K., Blood 113 (10), 2245-2255 (2009)
Background Reference 02
Qin, Y., Leuk. Res. 33 (3), 384-390 (2009)
Background Reference 03
Neumann, E., Cancer Res. 58 (18), 4090-4095 (1998)
Other Product Names
Melanoma antigen preferentially expressed in tumors, Opa-interacting protein 4, OIP-4, Preferentially expressed antigen of melanoma, PRAME, MAPE, OIP4
Tested Applications
WB, IHC-P, Flow
Protein ID
6685631
Physical Properties
Liquid

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