IL1RN Antibody

• Background:

  The protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of its gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.

• NCBI Gene ID:

  3557

• Swiss Prot:

  P18510

• Accession Number:

  P18510

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This IL1RN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-177 amino acids from the C-terminal region of human IL1RN.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  20 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  IL1RN

• NCBI Official Name:

  Interleukin-1 receptor antagonist protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kumar, S., Biochem. Biophys. Res. Commun. 387 (3), 456-460 (2009) Rechcinski, T., Kardiol Pol 67 (6), 601-610 (2009)

• Other Product Names:

  Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA

• Tested Applications:

  WB, IF, Flow

• Protein ID:

  124312

• Physical Properties:

  Liquid