Products for Research Use Only
RegisterLogin

OAS1 Antibody

CAT: 0223-62-189Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-62-189Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP (A2'P5'A) N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
NCBI Gene ID
4938
Swiss Prot
P00973
Accession Number
P00973
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This OAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human OAS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Symbol
OAS1
NCBI Official Name
2'-5'-oligoadenylate synthase 1
NCBI Organism
Homo sapiens
Background Reference 01
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .
Background Reference 02
Sarkar, S.N., et al., J. Biol. Chem. 274 (36) :25535-25542 (1999) .
Background Reference 03
Ghosh, A., et al., J. Biol. Chem. 272 (52) :33220-33226 (1997) .
Background Reference 04
Ghosh, S.K., et al., J. Biol. Chem. 266 (23) :15293-15299 (1991) .
Other Product Names
2'-5'-oligoadenylate synthase 1, (2-5') oligo (A) synthase 1, 2-5A synthase 1, E18/E16, p46/p42 OAS, OAS1, OIAS
Tested Applications
WB, IHC-P
Protein ID
296439492
Physical Properties
Liquid

Related Products

CatalogName
43-481POAS1 Peptide
62-190OAS3 Antibody
7775-01mgOASL Antibody
43-531OAS2 Antibody
43-511OAS3 Antibody
23-868OAS3 Antibody
7775-002mgOASL Antibody
43-520OAS2 Antibody
7775-01OASL Antibody
43-531POAS2 Peptide

Alternative Products

CatalogName
70R-9084OAS1 antibody
ABD7760OAS1 Antibody

Popular Products