MAGEA12 Antibody

CAT: 0223-62-151Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-151Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAGEA12 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This gene is expressed in various tumors and tumor cell lines from different tissue origins, but not detected in normal tissues, except testis. The function of this gene is unknown. This and other MAGE genes form a gene cluster at chromosome Xq28 region.
NCBI Gene ID
4111
Swiss Prot
P43365
Accession Number
P43365
Host
Rabbit
Reactivity
Human
Immunogen
This MAGEA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Symbol
MAGEA12
NCBI Official Name
Melanoma-associated antigen 12
NCBI Organism
Homo sapiens
Background Reference 01
Mallon, A.M., et al., Genome Res. 10 (6) :758-775 (2000) .
Background Reference 02
Rogner, U.C., et al., Genomics 29 (3) :725-731 (1995) .
Background Reference 03
Ding, M., et al., Biochem. Biophys. Res. Commun. 202 (1) :549-555 (1994) .
Background Reference 04
De Smet, C., et al., Immunogenetics 39 (2) :121-129 (1994) .
Other Product Names
Melanoma-associated antigen 12, Cancer/testis antigen 112, CT112, MAGE-12 antigen, MAGE12F antigen, MAGEA12, MAGE12
Tested Applications
WB, IHC-P
Protein ID
14286145
Physical Properties
Liquid

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