Leptin Antibody

• Background :

  Leptin (LEP) is an adipocyte-secreted protein that regulates body fat and endocrine functions. Leptin is similar to the mouse obesity protein encoded by the obese gene (ob) . In mouse studies, mutations in this gene are linked to severe and morbid obesity.

• NCBI Gene ID :

  3952

• Swiss Prot :

  P41159

• Accession Number :

  P41159

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This Leptin (LEP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the C-terminal region of human Leptin (LEP) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Neuroscience, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  19 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  LEP

• NCBI Official Name :

  Leptin

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Tank, J., et al., J. Clin. Endocrinol. Metab. 88 (10) :4955-4959 (2003) .

• Background Reference 02 :

  Silha, J.V., et al., Eur. J. Endocrinol. 149 (4) :331-335 (2003) .

• Background Reference 03 :

  Kazumi, T., et al., Metab. Clin. Exp. 52 (9) :1113-1116 (2003) .

• Background Reference 04 :

  Mullington, J.M., et al., J. Neuroendocrinol. 15 (9) :851-854 (2003) .

• Other Product Names :

  Leptin, Obese protein, Obesity factor, LEP, OB, OBS

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid