Leptin Antibody

CAT: 0223-62-142Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-142Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Leptin (LEP) is an adipocyte-secreted protein that regulates body fat and endocrine functions. Leptin is similar to the mouse obesity protein encoded by the obese gene (ob) . In mouse studies, mutations in this gene are linked to severe and morbid obesity.
NCBI Gene ID
3952
Swiss Prot
P41159
Accession Number
P41159
Host
Rabbit
Reactivity
Human
Immunogen
This Leptin (LEP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the C-terminal region of human Leptin (LEP) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
19 kDa
Fragment
Rabbit Ig
Symbol
LEP
NCBI Official Name
Leptin
NCBI Organism
Homo sapiens
Background Reference 01
Tank, J., et al., J. Clin. Endocrinol. Metab. 88 (10) :4955-4959 (2003) .
Background Reference 02
Silha, J.V., et al., Eur. J. Endocrinol. 149 (4) :331-335 (2003) .
Background Reference 03
Kazumi, T., et al., Metab. Clin. Exp. 52 (9) :1113-1116 (2003) .
Background Reference 04
Mullington, J.M., et al., J. Neuroendocrinol. 15 (9) :851-854 (2003) .
Other Product Names
Leptin, Obese protein, Obesity factor, LEP, OB, OBS
Tested Applications
WB, IF
Physical Properties
Liquid

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