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ICOS Antibody

CAT: 0223-62-139Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-139Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ICOS belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
NCBI Gene ID
29851
Swiss Prot
Q9Y6W8
Accession Number
Q9Y6W8
Host
Rabbit
Reactivity
Human
Immunogen
This ICOS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human ICOS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Symbol
ICOS
NCBI Official Name
Inducible T-cell costimulator
NCBI Organism
Homo sapiens
Background Reference 01
Okamoto, N., et al., Biochem. Biophys. Res. Commun. 310 (3) :691-702 (2003) .
Background Reference 02
Okamoto, T., et al., J. Rheumatol. 30 (6) :1157-1163 (2003) .
Background Reference 03
Riley, J.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (18) :11790-11795 (2002) .
Background Reference 04
Haimila, K.E., et al., Immunogenetics 53 (12) :1028-1032 (2002) .
Other Product Names
Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD278, ICOS, AILIM
Tested Applications
WB, IHC-P, Flow
Protein ID
50400701
Physical Properties
Liquid

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