PLA2G1B Antibody

• Background:

  PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets

• NCBI Gene ID:

  5319

• Swiss Prot:

  P04054

• Accession Number:

  P04054

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This PLA2G1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the C-terminal region of human PLA2G1B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  16 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PLA2G1B

• NCBI Official Name:

  Phospholipase A2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Xu, W., et al. J. Biol. Chem. 284 (24) :16659-16666 (2009)

• Background Reference 02:

  Han, C., et al. J. Cell. Biochem. 105 (2) :534-545 (2008)

• Background Reference 03:

  Kao, W.T., et al. Lipids Health Dis 7, 20 (2008)

• Other Product Names:

  Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B, PLA2G1B, PLA2, PLA2A, PPLA2

• Tested Applications:

  WB, Flow

• Protein ID:

  129404

• Physical Properties:

  Liquid