ENPP2 Antibody

CAT: 0223-61-553Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-553Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. This protein is secreted and further processed to make the biologically active form.
NCBI Gene ID
5168
Swiss Prot
Q13822
Accession Number
Q13822
Host
Rabbit
Reactivity
Human
Immunogen
This ENPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the Central region of human ENPP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
99 kDa
Fragment
Rabbit Ig
Symbol
ENPP2
NCBI Official Name
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
NCBI Organism
Homo sapiens
Background Reference 01
Kawagoe H., Soma O., Goji J., Nishimura N., Narita M., Genomics 30:380-384 (1995)
Background Reference 02
Nam S.W., Clair T., Kim Y.S., McMarlin A., Cancer Res. 61:6938-6944 (2001)
Background Reference 03
The MGC Project Team Genome Res. 14:2121-2127 (2004)
Other Product Names
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, Autotaxin, Extracellular lysophospholipase D, LysoPLD, ENPP2, ATX, PDNP2
Tested Applications
WB, IHC-P, Flow
Protein ID
290457674
Physical Properties
Liquid

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