PPAT Antibody

• Background:

  PPAT is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis.

• NCBI Gene ID:

  5471

• Swiss Prot:

  Q06203

• Accession Number:

  Q06203

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-205 amino acids from the Central region of human PPAT.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  57 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPAT

• NCBI Official Name:

  Amidophosphoribosyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bera, A.K., J. Biol. Chem. 274 (51), 36498-36504 (1999)

• Background Reference 02:

  Stanley, W., Cytogenet. Cell Genet. 22 (1-6), 228-231 (1978)

• Other Product Names:

  Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPAT, PPAT, GPAT

• Tested Applications:

  WB

• Protein ID:

  548638

• Physical Properties:

  Liquid