Vimentin Antibody

• Background:

  Along with the microfilaments (actins) and microtubules (tubulins), the intermediate filaments represent a third class of well-characterized cytoskeletal elements. The subunits display a tissue-specific pattern of expression. Desmin (MIM 125660) is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.

• NCBI Gene ID:

  7431

• Swiss Prot:

  P08670

• Accession Number:

  P08670

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Vimentin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-181 amino acids from the Central region of human Vimentin.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse, Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  54 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  VIM

• NCBI Official Name:

  Vimentin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Whipple, R.A., Cancer Res. 68 (14), 5678-5688 (2008)

• Background Reference 02:

  Garcia-Verdugo, I., Biochemistry 47 (18), 5127-5138 (2008)

• Background Reference 03:

  Merdes, A., J. Cell Biol. 115 (2), 397-410 (1991)

• Other Product Names:

  Vimentin, VIM

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  55977767

• Physical Properties:

  Liquid