CHRM3 Antibody

• Background:

  The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

• NCBI Gene ID:

  1131

• Swiss Prot:

  P20309

• Accession Number:

  P20309

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CHRM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 382-416 amino acids from human CHRM3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  66 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  CHRM3

• NCBI Official Name:

  Muscarinic acetylcholine receptor M3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Peralta E.G., et al.EMBO J. 6:3923-3929 (1987) .

• Background Reference 02:

  Bonner T.I., et al.Neuron 1:403-410 (1988) .

• Background Reference 03:

  Kitano T., et al.Mol. Biol. Evol. 21:936-944 (2004) .

• Background Reference 04:

  Puhl H.L. III, et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.

• Other Product Names:

  Muscarinic acetylcholine receptor M3, CHRM3

• Tested Applications:

  WB

• Protein ID:

  113125

• Physical Properties:

  Liquid