CHRM3 Antibody

• Background :

  The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

• NCBI Gene ID :

  1131

• Swiss Prot :

  P20309

• Accession Number :

  P20309

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CHRM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 382-416 amino acids from human CHRM3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  66 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:2000

• Symbol :

  CHRM3

• NCBI Official Name :

  Muscarinic acetylcholine receptor M3

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Peralta E.G., et al.EMBO J. 6:3923-3929 (1987) .

• Background Reference 02 :

  Bonner T.I., et al.Neuron 1:403-410 (1988) .

• Background Reference 03 :

  Kitano T., et al.Mol. Biol. Evol. 21:936-944 (2004) .

• Background Reference 04 :

  Puhl H.L. III, et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.

• Other Product Names :

  Muscarinic acetylcholine receptor M3, CHRM3

• Tested Applications :

  WB

• Protein ID :

  113125

• Physical Properties :

  Liquid