GALC Antibody

• Background:

  Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.

• NCBI Gene ID:

  2581

• Swiss Prot:

  P54803

• Accession Number:

  P54803

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GALC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 26-56 amino acids from human GALC.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  77 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GALC

• NCBI Official Name:

  Galactocerebrosidase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Luzi P., et al.Genomics 26:407-409 (1995) .

• Background Reference 02:

  Sakai N., et al.Biochim. Biophys. Acta 1395:62-67 (1998) .

• Background Reference 03:

  Ota T., et al.Nat. Genet. 36:40-45 (2004) .

• Background Reference 04:

  Heilig R., et al.Nature 421:601-607 (2003) .

• Other Product Names:

  Galactocerebrosidase, GALCERase, 3.2.1.46, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase, GALC

• Tested Applications:

  WB, Flow

• Protein ID:

  229462868

• Physical Properties:

  Liquid