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GALC Antibody

CAT: 0223-61-308Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-308Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.
NCBI Gene ID
2581
Swiss Prot
P54803
Accession Number
P54803
Host
Rabbit
Reactivity
Human
Immunogen
This GALC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 26-56 amino acids from human GALC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Symbol
GALC
NCBI Official Name
Galactocerebrosidase
NCBI Organism
Homo sapiens
Background Reference 01
Luzi P., et al.Genomics 26:407-409 (1995) .
Background Reference 02
Sakai N., et al.Biochim. Biophys. Acta 1395:62-67 (1998) .
Background Reference 03
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 04
Heilig R., et al.Nature 421:601-607 (2003) .
Other Product Names
Galactocerebrosidase, GALCERase, 3.2.1.46, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase, GALC
Tested Applications
WB, Flow
Protein ID
229462868
Physical Properties
Liquid

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