FBXO22 Antibody

• Background:

  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene.

• NCBI Gene ID:

  26263

• Swiss Prot:

  Q8NEZ5

• Accession Number:

  Q8NEZ5

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This FBXO22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the C-terminal region of human FBXO22.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FBXO22

• NCBI Official Name:

  F-box only protein 22

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Borziak, K., et al. Bioinformatics 23 (19) :2518-2521 (2007)

• Background Reference 02:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 03:

  Winston, J.T., et al. Curr. Biol. 9 (20) :1180-1182 (1999)

• Background Reference 04:

  Cenciarelli, C., et al. Curr. Biol. 9 (20) :1177-1179 (1999)

• Other Product Names:

  F-box only protein 22, F-box protein FBX22p44, FBXO22, FBX22

• Tested Applications:

  WB

• Protein ID:

  30580428

• Physical Properties:

  Liquid