USP1 Antibody

• Background:

  Deubiquitinating enzymes (DUBs) are capable of producing a free ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins in cells. DUBs possess conserved catalytic regions known as the 'cys domain' and the 'his domain.' There are 2 distinct families of DUBs: ubiquitin-specific processing proteases (UBPs, or USPs) and ubiquitin C-terminal hydrolases (UCHs) .

• NCBI Gene ID:

  7398

• Swiss Prot:

  O94782

• Accession Number:

  O94782

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This USP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 607-637 amino acids from the C-terminal region of human USP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  88 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  USP1

• NCBI Official Name:

  Ubiquitin carboxyl-terminal hydrolase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Puente, X.S., et al., Nat. Rev. Genet. 4 (7) :544-558 (2003) .

• Background Reference 02:

  Fujiwara, T., et al., Genomics 54 (1) :155-158 (1998) .

• Background Reference 03:

  D'Andrea, A., et al., Crit. Rev. Biochem. Mol. Biol. 33 (5) :337-352 (1998) .

• Other Product Names:

  Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid