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HIP2 Antibody

CAT: 0223-61-078Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-078Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
NCBI Gene ID
3093
Swiss Prot
P61086
Accession Number
P61086
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This HIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-139 amino acids from the Central region of human HIP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
UBE2K
NCBI Official Name
Ubiquitin-conjugating enzyme E2 K
NCBI Organism
Homo sapiens
Background Reference 01
Furukawa, Y., et al., Electrophoresis 21 (2) :338-346 (2000) .
Background Reference 02
Kikuchi, J., et al., Arterioscler. Thromb. Vasc. Biol. 20 (1) :128-134 (2000) .
Background Reference 03
Petersen, A., et al., Exp. Neurol. 157 (1) :1-18 (1999) .
Background Reference 04
Kalchman, M.A., et al., J. Biol. Chem. 271 (32) :19385-19394 (1996) .
Other Product Names
Ubiquitin-conjugating enzyme E2 K, Huntingtin-interacting protein 2, HIP-2, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2 (25K), Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligase, UBE2K, HIP2, LIG
Tested Applications
WB, IHC-P, IF
Protein ID
46577658
Physical Properties
Liquid

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