CD3EAP Antibody

• Background:

  DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.

• NCBI Gene ID:

  10849

• Swiss Prot:

  O15446

• Accession Number:

  O15446

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CD3EAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human CD3EAP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  55 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CD3EAP

• NCBI Official Name:

  DNA-directed RNA polymerase I subunit RPA34

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)

• Background Reference 02:

  Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)

• Background Reference 03:

  Vangsted, A.J., et al. Haematologica 94 (9) :1274-1281 (2009)

• Background Reference 04:

  Nissen, K.K., et al. Anticancer Drugs 20 (3) :174-178 (2009)

• Other Product Names:

  DNA-directed RNA polymerase I subunit RPA34, A345, Antisense to ERCC-1 protein, ASE-1, CD3-epsilon-associated protein, CAST, CD3E-associated protein, RNA polymerase I-associated factor PAF49, CD3EAP, ASE1, CAST, PAF49

• Tested Applications:

  WB

• Physical Properties:

  Liquid