PRRX2 Antibody

• Background:

  The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.

• NCBI Gene ID:

  51450

• Swiss Prot:

  Q99811

• Accession Number:

  Q99811

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This PRRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human PRRX2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  27 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PRRX2

• NCBI Official Name:

  Paired mesoderm homeobox protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Background Reference 02:

  Eriksson, N., et al. PLoS Genet. (6), E1000993 (2010) :

• Background Reference 03:

  Tokutomi, Y., et al. Biochem. Biophys. Res. Commun. 364 (4) :822-830 (2007)

• Background Reference 04:

  Wissmuller, S., et al. Nucleic Acids Res. 34 (6) :1735-1744 (2006)

• Other Product Names:

  Paired mesoderm homeobox protein 2, Paired-related homeobox protein 2, PRX-2, PRRX2, PMX2, PRX2

• Tested Applications:

  WB

• Protein ID:

  12644475

• Physical Properties:

  Liquid