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PRRX2 Antibody

CAT: 0223-60-703Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-703Size:400 µL
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Background
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
NCBI Gene ID
51450
Swiss Prot
Q99811
Accession Number
Q99811
Host
Rabbit
Reactivity
Mouse
Immunogen
This PRRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human PRRX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PRRX2
NCBI Official Name
Paired mesoderm homeobox protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 02
Eriksson, N., et al. PLoS Genet. (6), E1000993 (2010) :
Background Reference 03
Tokutomi, Y., et al. Biochem. Biophys. Res. Commun. 364 (4) :822-830 (2007)
Background Reference 04
Wissmuller, S., et al. Nucleic Acids Res. 34 (6) :1735-1744 (2006)
Other Product Names
Paired mesoderm homeobox protein 2, Paired-related homeobox protein 2, PRX-2, PRRX2, PMX2, PRX2
Tested Applications
WB
Protein ID
12644475
Physical Properties
Liquid

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