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ATP1B2 Antibody

CAT: 0223-60-685Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-685Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit.
NCBI Gene ID
482
Swiss Prot
P14415
Accession Number
P14415
Host
Rabbit
Reactivity
Human
Immunogen
This ATP1B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the C-terminal region of human ATP1B2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ATP1B2
NCBI Official Name
Sodium/potassium-transporting ATPase subunit beta-2
NCBI Organism
Homo sapiens
Background Reference 01
Floyd, R.V., et al. Reprod Sci 17 (4) :366-376 (2010)
Background Reference 02
Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)
Background Reference 03
Boer, K., et al. Brain Pathol. 20 (1) :234-244 (2010)
Background Reference 04
Tokhtaeva, E., et al. Biochemistry 48 (48) :11421-11431 (2009)
Other Product Names
Sodium/potassium-transporting ATPase subunit beta-2, Adhesion molecule in glia, AMOG, Sodium/potassium-dependent ATPase subunit beta-2, ATP1B2
Tested Applications
WB
Protein ID
125987795
Physical Properties
Liquid

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