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RGS13 Antibody

CAT: 0223-60-549Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-549Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.
NCBI Gene ID
6003
Swiss Prot
O14921
Accession Number
O14921
Host
Rabbit
Reactivity
Human
Immunogen
This RGS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human RGS13.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
19 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RGS13
NCBI Official Name
Regulator of G-protein signaling 13
NCBI Organism
Homo sapiens
Background Reference 01
Wang, J., et al. Carcinogenesis 31 (10) :1755-1761 (2010)
Background Reference 02
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 03
Bansal, G., et al. J. Immunol. 181 (11) :7882-7890 (2008)
Background Reference 04
Han, J.I., et al. J. Leukoc. Biol. 79 (6) :1357-1368 (2006)
Other Product Names
Regulator of G-protein signaling 13, RGS13, RGS13
Tested Applications
WB
Physical Properties
Liquid

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