TMPRSS6 Antibody

• Background:

  The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.

• NCBI Gene ID:

  164656

• Swiss Prot:

  Q8IU80

• Accession Number:

  Q8IU80

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TMPRSS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human TMPRSS6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  90 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TMPRSS6

• NCBI Official Name:

  Transmembrane protease serine 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Altamura, S., et al. Biochem. J. 431 (3) :363-371 (2010)

• Background Reference 02:

  Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16 (10) :770-777 (2010)

• Background Reference 03:

  De Falco, L., et al. Hum. Mutat. 31 (5), E1390-E1405 (2010) :

• Background Reference 04:

  Tanaka, T., et al. Blood 115 (1) :94-96 (2010)

• Other Product Names:

  Transmembrane protease serine 6, 3421-, Matriptase-2, TMPRSS6

• Tested Applications:

  WB

• Protein ID:

  209572718

• Physical Properties:

  Liquid