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TNPO1 Antibody

CAT: 0223-60-489Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-489Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.
NCBI Gene ID
3842
Swiss Prot
Q92973
Accession Number
Q92973
Host
Rabbit
Reactivity
Human
Immunogen
This TNPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-74 amino acids from the N-terminal region of human TNPO1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
102 kDa
Fragment
Rabbit Ig
Symbol
TNPO1
NCBI Official Name
Transportin-1
NCBI Organism
Homo sapiens
Background Reference 01
Fineberg, K., et al., Biochemistry 42 (9) :2625-2633 (2003) .
Background Reference 02
Nelson, L.M., et al., Virology 306 (1) :162-169 (2003) .
Background Reference 03
Le Roux, L.G., et al., J. Virol. 77 (4) :2330-2337 (2003) .
Background Reference 04
Limon, A., et al., J. Virol. 76 (21) :10598-10607 (2002) .
Other Product Names
Transportin-1, Importin beta-2, Karyopherin beta-2, M9 region interaction protein, MIP, TNPO1, KPNB2, MIP1, TRN
Tested Applications
WB, IHC-P, Flow
Protein ID
259016171
Physical Properties
Liquid

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