PPP2R5D Antibody

• Background:

  The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID:

  5528

• Swiss Prot:

  Q14738

• Accession Number:

  Q14738

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPP2R5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human PPP2R5D.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rb

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  70 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPP2R5D

• NCBI Official Name:

  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yu, U.Y., et al. BMB Rep 43 (4) :263-267 (2010)

• Background Reference 02:

  Reece, K.M., et al. Biochem. Biophys. Res. Commun. 386 (4) :582-587 (2009)

• Background Reference 03:

  Forester, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (50) :19867-19872 (2007)

• Background Reference 04:

  Sablina, A.A., et al. Cell 129 (5) :969-982 (2007)

• Other Product Names:

  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, PP2A B subunit isoform B'-delta, PP2A B subunit isoform B56-delta, PP2A B subunit isoform PR61-delta, PP2A B subunit isoform R5-delta, PPP2R5D

• Tested Applications:

  WB

• Protein ID:

  7387495

• Physical Properties:

  Liquid