PPP2R5C Antibody

• Background:

  The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID:

  5527

• Swiss Prot:

  Q13362

• Accession Number:

  Q13362

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPP2R5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human PPP2R5C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPP2R5C

• NCBI Official Name:

  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Anney, R., et al. Hum. Mol. Genet. 19 (20) :4072-4082 (2010)

• Background Reference 02:

  Lee, T.Y., et al. J. Biol. Chem. 285 (28) :21567-21580 (2010)

• Background Reference 03:

  Shouse, G.P., et al. Oncogene 29 (27) :3933-3941 (2010)

• Background Reference 04:

  Tung, H.Y., et al. FEBS Lett. 401 (2-3), 197-201 (1997) :

• Other Product Names:

  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, PP2A B subunit isoform B'-gamma, PP2A B subunit isoform B56-gamma, PP2A B subunit isoform PR61-gamma, PP2A B subunit isoform R5-gamma, Renal carcinoma antigen NY-REN-29, PPP2R5C, KIAA0044

• Tested Applications:

  WB

• Protein ID:

  116241235

• Physical Properties:

  Liquid