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PPP2R5C Antibody

CAT: 0223-57-430Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-430Size:400 µL
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Background
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
5527
Swiss Prot
Q13362
Accession Number
Q13362
Host
Rabbit
Reactivity
Human
Immunogen
This PPP2R5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human PPP2R5C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP2R5C
NCBI Official Name
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
NCBI Organism
Homo sapiens
Background Reference 01
Anney, R., et al. Hum. Mol. Genet. 19 (20) :4072-4082 (2010)
Background Reference 02
Lee, T.Y., et al. J. Biol. Chem. 285 (28) :21567-21580 (2010)
Background Reference 03
Shouse, G.P., et al. Oncogene 29 (27) :3933-3941 (2010)
Background Reference 04
Tung, H.Y., et al. FEBS Lett. 401 (2-3), 197-201 (1997) :
Other Product Names
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, PP2A B subunit isoform B'-gamma, PP2A B subunit isoform B56-gamma, PP2A B subunit isoform PR61-gamma, PP2A B subunit isoform R5-gamma, Renal carcinoma antigen NY-REN-29, PPP2R5C, KIAA0044
Tested Applications
WB
Protein ID
116241235
Physical Properties
Liquid

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GWB-MU971HPPP2R5C Antibody

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