FGF20 Antibody

• Background:

  The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.

• NCBI Gene ID:

  26281

• Swiss Prot:

  Q9NP95

• Accession Number:

  Q9NP95

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This FGF20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human FGF20.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FGF20

• NCBI Official Name:

  Fibroblast growth factor 20

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  De Mena, L., et al. Neurosci. Lett. 479 (1) :22-25 (2010)

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Lemaitre, H., et al. J. Neurosci. 30 (17) :5992-5997 (2010)

• Background Reference 04:

  Maity, H., et al. Curr Pharm Biotechnol 10 (6) :609-625 (2009)

• Other Product Names:

  Fibroblast growth factor 20, FGF-20, FGF20

• Tested Applications:

  WB

• Protein ID:

  13626702

• Physical Properties:

  Liquid