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FGF20 Antibody

CAT: 0223-60-454Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-454Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.
NCBI Gene ID
26281
Swiss Prot
Q9NP95
Accession Number
Q9NP95
Host
Rabbit
Reactivity
Mouse
Immunogen
This FGF20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human FGF20.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FGF20
NCBI Official Name
Fibroblast growth factor 20
NCBI Organism
Homo sapiens
Background Reference 01
De Mena, L., et al. Neurosci. Lett. 479 (1) :22-25 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Lemaitre, H., et al. J. Neurosci. 30 (17) :5992-5997 (2010)
Background Reference 04
Maity, H., et al. Curr Pharm Biotechnol 10 (6) :609-625 (2009)
Other Product Names
Fibroblast growth factor 20, FGF-20, FGF20
Tested Applications
WB
Protein ID
13626702
Physical Properties
Liquid

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